27 March 2020

• Phase I trial of Oxford’s adenovirus COVID-19 vaccine begins.
• Boris Johnson, the United Kingdom (UK) Prime Minister, tests positive for COVID-19.
• Three groups of researchers publish reports describing the structure of the receptor-binding domain of the SARS-CoV-2 spike protein (which binds to the ACE2 cell receptor); this is an important target for COVID-19 drug development. sources 1,2,3

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